Myth: We Don’t Know the Long-Term Effects of the Vaccine

A common argument against the COVID-19 vaccines is that we do not know the long-term effects of them. That’s simply another misrepresentation of the facts by those who are trying to either minimize COVID or are antivaxxers.

One thing we know from all other vaccines is that any adverse effects occur within eight weeks of administration. There is no reason to think that would be any different with the mRNA vaccines and this will explain why.

Below are the ingredients of the mRNA vaccines, shown as screenshots with links to the source. I have included the first line of the next section at the bottom of each image to show that these are the entire ingredient sections for both. My narrative continues at the heading “Lipids.”

Moderna (Spikevax)

Pfizer-Biontech (Comirnaty)

Lipids

The lipids are primarily a delivery vehicle to get the mRNA into a cell intact. mRNA is a very delicate molecule and would be quickly broken down by the body if it were injected without the liquid nanoparticles (LNPs) that contain it. The different ones have different functions, and more information is available here. They mimic the cell membranes that are already in the cells of the body. Part of the reason that these vaccines have to be stored at such low temperatures is because the mRNA is so fragile.

  • ((4-hydroxybutyl)azanediyl)bis(hexane-6,1-diyl)bis(2-hexyldecanoate)
  • 2 [(polyethylene glycol)-2000]-N,N-ditetradecylacetamide
  • 1,2-Distearoyl-sn-glycero-3-phosphocholine
  • SM-102
  • polyethylene glycol [PEG] 2000 dimyristoyl glycerol [DMG]
  • 1,2-distearoyl-sn-glycero-3-phosphocholine [DSPC])
  • cholesterol

All of these are broken down into their component parts, just like all of the lipids in your body, so we know the long-term effects of the LNPs – none.

Inorganic components

Acid Stabilizers (alternate names in parentheses)

Salts and Sugars

  • Dibasic sodium phosphate dihydrate. One of the brand names is Aminosyn, which is part of total parenteral nutrition (TPN) given intravenously for those who cannot eat food. Long-term effects: none.
  • Monobasic potassium phosphate (monopotassium phosphate). Another salt used in TPN as above. Long-term effects: none.
  • Potassium chloride. This is often given intravenously for low potassium levels. Long-term effects: none.
  • Sodium chloride. This is table salt. As a solution in healthcare, it’s given intravenously as normal saline. Long-term effects: None.
  • Sucrose. This is table sugar. When injected, it doesn’t get metabolized and gets excreted in the urine. Long-term effects: None.

mRNA

Since the side ingredients in the mRNA vaccines do not have any long-term consequences as has been established by their use for decades, what about the mRNA itself? This takes a little bit of understanding of biochemistry.

A very simple explanation of mRNA is that it is a blueprint to make a protein. The human body makes over 100,000 different proteins, so each of us has quite a large library of mRNA instructions already encoded within each cell.

Here’s a brief description of the normal process.

  • The DNA within the nucleus of the cell is partially unzipped.
  • A process called transcription copies one section of one side of the DNA into mRNA
  • The mRNA leaves the nucleus and enters the cytoplasm of the cell.
  • Another molecule (tRNA) reads the code of the mRNA that is used in a ribosome to make a protein in a process called translation

The ONLY difference with the mRNA in the vaccine is that it doesn’t originate from the nucleus of the cell. The mRNA breaks down into its component nucleic acids and amino acids within a few weeks, just like normal mRNA. Long-term effects: None.

Another argument related to the vaccine itself is that it travels through the body. That’s patently false too. It pretty much remains in the muscle and local lymph nodes at the injection site.

The Spike Protein

Of course, the next argument will be that the spike protein causes long-term damage. First, the vaccine-induced spike protein is slightly different than the spike protein of the virus, so making the claim that the spike in the vaccine acts the same as that of the virus is a stretch.

The mRNA in the vaccine is ONLY making the spike protein. When the SARS-CoV-2 virus infects a cell, it hijacks the machinery of the cell to make many other proteins to both replicate the virus and more importantly, to cause the cell to release replicated virus. This takes a host of other proteins to accomplish that feat.

Part of the reason that this is important is because the spike protein can be thought of as “sticky” as it relates to the cell membrane. In essence, most remain trapped by the cell that produced it, kind of like a dog on a very short leash.

The body recognizes this protein as not being normal and ramps up antibody production to alert the immune system should it come across that protein again in the future. It also destroys the spike protein within a few weeks. Long-term effects: none.

Think about what would happen if our bodies never got rid of proteins produced by mRNA. It would kill us.

I thought some people might be interested in seeing how proteins are produced. This is a little more detail than I provided in writing, but it is a very good animation of the process.

Conclusion

Anyone who is saying that we don’t know the long-term effects of the vaccine are simply repeating misinformation and are not knowledgeable about cell biology. Take anything that they say with a grain of salt, because they are likely just repeating propaganda.