A Grim Future

A figure in a dark cloak holding a scythe stands outside a hospital entrance, symbolizing a looming threat or challenge to healthcare.

My current role is as director of infection prevention for a hospital system. I do this kind of work as a traveler, so I see the best and worst practices in many places.

Today I was working on our healthcare associated infection (HAI) plan for the execs. Hospitals routinely monitor rates of HAI and work to reduce them. I wanted to include a section about how COVID is going to make HAI rates climb. This is what I wrote.


One important measure to keep in mind is the impact COVID is going to have on HAI rates due to the immune dysregulation and vascular damage it causes. I had expected HAI rates to climb as a result and pulled UK data on MRSA bacteremia in late 2024. I did not use 2020 data for pre-COVID and pandemic trends because of the high number of confounding variables that year. The trend lines painted a picture far worse than expected.

Graph showing MRSA bacteremia cases in the UK from 2016 to 2024, depicting trends with a mix of bar and line charts. The bars represent the number of cases, while the lines indicate the rates and trends over time, including pre-COVID and COVID trends.
The blue columns is the incidence of MRSA bacteremia. The green dotted line is the trend pre pandemic. The red dotted line is the trend since the pandemic.

Eventually data was published that showed similar trends with other organisms.

Graph depicting the 12-month rolling percent change in infection rates for various organisms including MRSA, MSSA, E. coli, Klebsiella spp., C. difficile, and P. aeruginosa from December 2012 to December 2024.
Typically, each line would hover around the 0% line with some minor fluctuation up and down. The fact that all of these are now climbing, most alarmingly among a couple that had been declining, is extremely disturbing.
A detailed chart displaying rolling monthly totals of lab confirmed cases for various pathogens from 2015 to 2024 in England, highlighting significant trends and fluctuations in infection rates.

It’s not just adults. These problems are showing up in pediatric populations, such as this study from JAMA around Group A strep infections.

Graph depicting the incidence of infections by age group and season from 1992 to 2023, highlighting trends in pediatric populations.

This is also reflected in pediatric influenza deaths by season. One doesn’t even need trend lines to see a big difference in the patterns before COVID and now.

As part of assessing cognitive ability of HCWs, I used Google Search Trends to extrapolate some answers to brain function pre-COVID versus current, showing similar trends. This suggests that procedural errors that could result in HAI will become more frequent. In this case, I used a simple cutoff of March of 2021 to account for the lagging effects of problems like this after acute infections.

A graph depicting Google Search Trends over time, showing the rise in searches related to COVID, brain fog, cognitive ability, and other cognitive functions, with a significant increase noted after March 2021.
The dotted lines are the trends pre-pandemic. The solid lines represent the trend lines starting since March 2021, which is about the time that people might have started seeing these kinds of issues in themselves or others.

In the current era, maintaining infection rates may become challenging. This is compounded by the recent gutting of the CDC, which would normally provide data at a national level, although it lags far more than the data that is provided by the UK. It may be worth thinking of HAI goals in the framework of increasing at slower rates than the national average.

The chronic disease sequelae from COVID are going to place a high burden on healthcare in the coming years, particularly in combination with the aging baby boomer population. Further, these sequelae will hit healthcare workers as well, which will reduce the size of the HCW labor force. That will likely lead to more HCWs leaving the field from burnout, causing a positive feedback loop.

The excess burden of this combined with multiple infections will hasten this outcome. The reinfection burden was recognized back in 2022.

Bar graph showing excess burden of various health conditions related to infections, with color-coded data points for one, two, and three or more infections. Conditions include hospitalization, cardiovascular issues, kidney problems, and mental health effects.

We are facing a very harsh reality that much of the population is either ignorant about or is living in denial about. Neither changes the outcome. All we can do is try to mitigate the worst of this, but I have my doubts that we have the willpower (or current leadership) to do so.

Who needs horror movies when we have reality?

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